Anticorps monoclonaux anti-ferroportine 1 et leurs utilisations

Anti-ferroportin 1 monoclonal antibodies and uses thereof

Abstract

Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo.

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